Early white matter changes in Wilson disease.
نویسندگان
چکیده
We describe a 12 years old male who presented with one year history of cognitive decline with extrapyramidal features. Wilson disease was diagnosed on basis of biochemical studies and MRI. MRI showed increased signal intensity on T2 weighted images in basal ganglia and supratentorial with infratentorial gray and white matter. Our patient developed white matter changes early in course of disease.
منابع مشابه
MR of the base of the pons in Wilson disease.
The authors describe unusual MR findings in three patients with Wilson disease, eg, white matter changes in the base of the pons, and speculate whether the changes are caused by Wilson disease or by concomitant disease, and whether the pontine lesions they observed are primary or related to lesions located more rostrally.
متن کاملThe Participation of Three Brain Tissues in Alzheimer’s disease Diagnosis from Structural MRI
Alzheimer’s disease (AD) is a progressive and irreversible disease which gradually makes patients unable to do their daily routines. Although the present treatments can not cure the disease completely, its early detection can reduce symptoms and enhance the patients’ life quality. In the current literature, using the grey matter (GM) tissue which is known as an appropriate biomarker is highly c...
متن کاملThe Clinical Manifestations, Treatment Efficacy and Adverse Drug Reactions in 62 Iranian Child with Wilson Disease
Introduction: The Wilson disease is an autosomal recessive disease in which the liver, central nervous system, eyes, blood and other parts of the body involved. Timely diagnosis and appropriate treatment of the disease requires awareness of the clinical presentations of this disease in children.Methods: This case series study included 62 patients with Wilson disease who admitted to children's M...
متن کاملCranial MR in Wilson disease: abnormal white matter in extrapyramidal and pyramidal tracts.
PURPOSE To describe abnormal white matter in the brain on MR in Wilson disease and to compare with anatomic location of white matter tracts. METHODS Forty-six patients with Wilson disease were examined. Axial T1-weighted inversion-recovery, axial T2-weighted spin-echo, and coronal T2*-weighted gradient-echo MR images were performed. Imaging studies were compared with clinical data. RESULTS ...
متن کاملP27: Brain Network as a Pivotal Part in Intelligence Function
Neuroimaging findings have proposed that some brain regions including the precuneus, posterior cingulate, and medial prefrontal cortex play an essential role of a structural core in the brain. Network organization endures rapid alterations in development with changes in axonal synaptic connectivity, white matter volume, and the thickness of corresponding cortical regions. Structural maturation ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- The Journal of the Association of Physicians of India
دوره 52 شماره
صفحات -
تاریخ انتشار 2004